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Brent Appleton

Senior Director
Immunoregulatory Sequence Program

United States

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Brent Appleton - Professional Summary:   


Licensed to practice medicine in the states of Michigan, California, and Washington, Dr. Brent Appleton brings more than a decade of experience to his work as a physician, clinical researcher, and medical educator. Dr. Appleton earned his Doctor of Medicine from the University of Ottawa in Ontario and went on to earn board certification from the American Board of Internal Medicine, with a Subspecialty in Rheumatology. He also holds a Master of Arts in Clinical Research Design and Statistical Analysis and a Bachelor of Science in Neuroscience. Dr. Appleton completed his residency in categorical internal medicine at the Cleveland Clinic Foundation in Ohio and an additional fellowship in rheumatology at the University of Michigan in Ann Arbor. 

As a medical researcher, Dr. Brent Appleton has presented abstracts at a variety of national and international conferences and symposia such as the European League against Rheumatism (EULAR) Annual European Congress of Rheumatology in Stockholm, Sweden, and the Annual Scientific Meeting of the American College of Rheumatology in San Antonio, Texas. Clinical results and medical articles that Dr. Appleton has either authored or coauthored include “The Safety of Extended Treatment with Anakinra in Patients with Rheumatoid Arthritis” in the 2006 Annals of the Rheumatic Diseases and “The Development of Systemic Sclerosis (Scleroderma) Following Augmentation Mammoplasty” in the 1993 Journal of Rheumatology. 

As an educator, Dr. Brent Appleton has served as a Clinical Assistant Professor at the University of Washington in Seattle and as a Lecturer in the Division of Rheumatology at the University of Michigan Medical School. While at Michigan, Dr. Appleton was honored with the Thomas D. Palella Excellence in Teaching Award. He is a Fellow at the American College of Rheumatology, an organization that advances rheumatology treatment through education, research, advocacy, and practice support.


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